Villians in Japanese manga, anime, games?

[Mahoujin Tsukai]

Anybody can name some notorious villians from Japanese manga, anime and games?

 

[Glenn]

武装錬金のパピヨンマスクこと蝶野攻爵 (Papillon Mask, a.k.a. Chôno Kôshaku of Busô Renkin). Most interesting villain of all time.

 

[Nuala]

Video Games: Sephiroth
Anime: Vicious from Cowboy Bebop
Manga: Uchiha Madara from Naruto

 

[Mahoujin Tsukai]

I'll name Zaboera (ザボエラ) from the manga (and anime) Dragon Quest dai no daiboken (ダイの大冒険).