Both are hard without context, but here's my thoughts:
引きずりすぎだよ。
引きずる is like 'drag', right? With ―過ぎる, It becomes 'you've dragged ___ too far'. You could also use it to mean 'you've taken ___ too far' I think. I don't watch anime really, but I'm guessing the context you heard this in was probably someone yelling at someone else that they have taken something too far, or said too much.
ズレてるよそれ。
ずれる means 'out of place'. For example, 事務所に来て金庫の位置が前日より少しずれているのに気づいた。 (I came to the office and noticed that the safe was in a slightly different place than the day before.) In your context, however, it is more likely to be something like お前の言った事は今の話題よりずれてるんだよ! (What you said is off what we are talking about! / Get back on topic!) But I'm not so sure about this one. It isn't a very strong phrase, so if someone yelled it it would sound weird. Depends on context. Mind giving a bit of info on the scene you heard them?