Konnichiwa zeroh4nter-san!
Main text
"ふたりとも、使いどころさえ間違わんかったら有能なんやけどなぁ……"
Translation.
"If you can assign them missions well, they will do great..."
or
"If you assign them tasks that match their abilities, they will perform optimally..."
It would normally be followed by the following sentences.
"But if you don't assign them missions well, they won't reach their full potential".
or
"But if you don't assign them missions well, they will not perform as expected."
使いどころ means "duties appropriate to ability".
間違わんかったら means "don't make a mistake".
(間違えなければ)
In this case, the wrong mission was given, causing it to go out of control.
NANGI