I didn't think so until I joined JREF and read a few posts from people living in Europe and/or US saying they couldn't handle it.
After that, I've asked some people I met in the US how they felt when they tasted wasabi for the first time. Quite a few told me it took time to appreciate it.
So, I'm not saying Westerners in general can't handle wasabi. My observation was based strictly on first-timers.