Yes, that's about right.
Not exactly antonym, but there is 疎外感 (sogai-kan, sense of alienation)
未知 literally means not yet known but can also be "infinite" in the positive sense.
So, 未知の生き甲斐 can be what you suggest or "infinite" purpose in life, depending on context.
Typical example is 未知の可能性 (infinite possibilities).
HTH!