Hello Princess,
Have you browsed around on this site for info on living arrangements, etc...? This is a great resource for Japan info, so if you look at the articles section, or make use of the search function on JREF, you should be able to find tons of info on life in Japan.
Covid has shaken everything up, and it has particularly shaken up travel to/from Japan for foreign nationals. No telling how it will affect the long-term employment situation. "Work From Home" was not at all an option for most companies, but now it is becoming more widespread. This is good news because it frees you from having to live in Tokyo, or close to a train/subway station. It gives you a huge amount of options. Bear in mind, raising a non-Japanese kid in Japan means you probably want to be someplace where there are other kids/families like yours, otherwise the feeling of isolation can be very intense. Its nice for you, but especially nice for your kids, to have access to someone from a similar background. So if you are within, say, an hour of Tokyo or Yokohama or Osaka/Kobe/
Kyoto you ameliorate this problem pretty well. Fukuoka and Sendai, or
Hokkaido are also options if you are a bit more adventurous. However, the farther you are away from Tokyo or Osaka, the more you may inadvertently be limiting your options for jobs, education, housing, health resources, etc... And if you have family in the US, whom you will want to visit from time-to-time, the farther you are from an international airport more expensive and exhausting it becomes to get to/from the airport.